Choline Chloride Overview

Choline chloride or N-(2-Hydroxyethyl) trimethylammonium chloride is an organic compound and a quaternary ammonium salt. The counterion is chlorine. In the laboratory choline can be prepared by methylation of dimethylethanolamine with methyl chloride. In the industrial Davy process choline chloride is produced from ethylene oxide, hydrochloric acid, and trimethylamine. Alternative names are hepacholine, biocolina and lipotril.

Choline is a quaternary ammonium compound having a hydroxyl substituent with general formula, (CH3)3N+CH2CH2OHX- . It is a strongly basic hygroscopic amine substance distributed widely in plant and animal tissues. It is often referred to vitamin B complex.

Choline chloride is mainly used to stimulate the growth of the domestic animals, boosting up the body’s immunity function. It has prominence effects on improving the quality and quantity of egg and meat. The many year’s application shows that the product is the necessary additive of the domestic animal’s foodstuff.

Choline is one of the vitamins, and is the main components of lecithin. The young poultry is not of the ability of synthesizing choline. All the necessity relies on the supply of food. Though food in nature is not lacking of the choline, the applying of the choline chloride will guarantee the rapid growth of the animals

Choline chloride is mass produced and is an important additive in feed especially for chicken where it accelerates growth. With urea it forms a deep eutectic solvent. Other commercial choline salts are choline hydroxide and choline bitartrate. In food stuffs the compound is often present as phosphatidylcholine.

Choline is necessary for chicken (the content is extremely low in the grist)
, for it can synthesize amino acid and lecithin then to be sent to the inner body of the chickens, and prevent from the accumulation of fat in liver and kidney, accelerate the growth of the chickens, and improve the laying rate and hatchablilty. Lacking of the choline in the food stuff, will lead to the hypogenesis, coarseness of leather, chondrify, feebleness and illability of mink, pig, rabbit, cow, etc. Adding choline in the bait of all kinds of fish and shrimp, the growth of fish and shrimp will be accelerated, then high yielding will be obtained.

Choline chloride recommended adding amount: Generally, 1 kg should be added into per 1000 kg food stuff. The amount should be increased for the young poultry. Take the circumstance into consideration.

choline chloride note: This product is of extremely hygroscopicity, closely protect in the dry place.

PRODUCT IDENTIFICATION
CAS NO. 67-48-1
EINECS NO. 200-655-4
FORMULA HOCH2CH2N(CH3)3Cl
MOL WT. 139.63
H.S. CODE 2923.10
TOXICITY Oral rat LD50: 3400 mg/kg
SYNONYMS

(2-Hydroxyethyl)trimethylammonium chloride; Hepacholine; Biocolina; lipotril; Choline hydrochloride; Cholinium chloride; (2-Hydroxyethyl)trimethylammonium chloride; Choline hydrochloride; 2-Hydroxy-N,N,N-trimethylethanaminium Chloride; Chloride De Choline (French); Biocolina; N,N,N-Trimethyl-2-hydroxyethylammonium Chloride; 2-Hydroxy-N,N,N-trimethylethanaminium, Chloride;

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE White crystals, Slight amine odor
MELTING POINT 303 – 305 °C
SOLUBILITY IN WATER Very soluble
pH neutral to slightly acid
NFPA RATINGS Health: 1 Flammability: 1 Reactivity: 0
STABILITY Stable under ordinary conditions

SALES SPECIFICATION
CORN COB TYPE
CONTENT 50.0% or 60.0% min
LOSS ON DRYING 4.0% max
PARTICLE SIZE 85% min ( 20 mesh)
SILICA TYPE
CONTENT 50.0% min
LOSS ON DRYING 2.0% max
PARTICLE SIZE 95% min ( 20 mesh)
AQ. SOLUTION
CONTENT 70.0% or 75.0% min
HEAVY METALS 20ppm max
RESIDUE ON IGNITION 0.2% max
TRANSPORTATION
PACKING 25kgs in bag, 230kgs in drum
HAZARD CLASS Not regulated